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Damnacanthal, CAS No 477-84-9, Damnacanthal CAS No 477-84-9 manufacturer / supplier in China, offering Damnacanthal CAS No 477-84-9 for Traditional Medicine for Pharmaceuticals, Eugenol CAS: 97-53-0, Benzophenone-6 CAS 131-54-4 and so on.

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Damnacanthal CAS No 477-84-9 for Traditional Medicine for Pharmaceuticals

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Min. Order: 100 MG
Port: Shenzhen, China
Production Capacity: 5000kgs Per Month
Payment Terms: L/C, T/T, Western Union, Paypal

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Basic Info
  • Certification: SGS
  • Function: Pharmaceuticals
  • Color: Orange-Yellow
  • Synonym: Damnacanthal
  • M.F: C16H10O5
  • Purity: 98%Min
  • Documents Available: Coa, MSDS, Nmr, HPLC
  • Shelf Life: 2 Years
  • Transport Package: 1kg/Bag, 25kgs Per Drum
  • Origin: Shenzhen of China
  • Environmental Protection: Yes
  • Appearance: Solid
  • Name: 3-Hydroxy-1-Methoxyanthraquinone-2-Aldehyde
  • CAS No: 477-84-9
  • Molecular Weight: 282.34
  • Solubility: Soluble to 25 mm in DMSO
  • Storage: -20csealed, Avoid Light, in N2
  • Trademark: Dieckamann
  • Specification: 1Kg/bag, 25kgs per drum
Product Description
Damnacanthal
Name     Damnacanthal   CAS No477-84-9
Synonmy M.FC16H10O5
AppearancePale yellow crystallineM.W    282.34
Storage4°C refrigerated,sealed avoid lightPurity98%min

Application: It is an anthraquinone which acts as a p56lck tyrosine kinase  inhibitor.It can be extracted from Morinda citrifolia.have long been used in traditional medicine for the treatment of cancer.

Description:
Damnacanthal is an anthraquinone which acts as a p56lck tyrosine kinase inhibitor. It can be extracted from Morinda citrifolia.  have long been used in traditional medicine for the treatment of cancer .  
 
Name3-Hydroxy-1-methoxyanthraquinone-2-aldehyde
SynonymDamnacanthal
Assay≥ 98%min
CAS477-84-9
Molecular formula:C16H10O5
Percentage Composition:C 68.09%; H 3.57%; O 28.34%
Melting Point:Mp 218-218.5ºC
Physical Description:Orange-yellow solid
Biological Sourceextracted from Morinda citrifolia.
primary target p56lck autophosphorylation
primary target IC50  17 nM against p56lck autophosphorylation
Packaging:Packaged under inert gas
Storage-20 °C, sealed, avoid light,in N2
UsageA cell-permeable, potent, reversible, and selective inhibitor of p56lck tyrosine kinase
The period of validity2 years
 
Overview
A cell-permeable, potent, reversible, and selective inhibitor of p56lck tyrosine kinase. Inhibits p56lck autophosphorylation (IC50 = 17 nM) and phosphorylation of an exogenous peptide by p56lck (IC50 = 620 nM). Exhibits over 100-fold greater selectivity for p56lck over PKA and PKC, 40-fold greater selectivity for p56lck over EGF receptor kinase, c-ErbB2, insulin receptor kinase, and PDGF receptor kinase, and 7 - 20-fold greater selectivity for p56lck over p60src and p59fyn. Inhibition of p56lck is not significantly affected by the presence of sulfhydryl reagents. Also known to have antimalarial properties and to reverse the phenotype of ras-transformed cells.
A cell-permeable, potent, reversible, and selective inhibitor of p56lck tyrosine kinase activity. Inhibits p56lck autophosphorylation (IC50 = 17 nM) and phosphorylation of an exogenous peptide by p56lck over PKA and PKC and >40 fold selectivity for p56lck over EGF, c-erbB2, insulin, and the PDGF receptor tyrosine kinases. In addition, damnacanthal exhibits 7-20 fold selectivity for p56lck over pp60src and pp59fyn. Inhibition of p56lck by damnacanthal appears to be reversible, not time-dependent and not significantly affected by the presence of sulfhydryl reagents. Also known to have antimalarial properties, and to reverse the phenotype of ras-transformed cells.
 
Application:
It have long been used in traditional medicine for the treatment of cancer .
 
Features :
1.Any inquiries will be replied within 12 hours.
2. Dedication to quality, supply & service.
3. Strictly on selecting raw materials.
4. OEM/ODM Available.
5. Reasonable & competitive price, fast lead time.
6. Sample is available for your evaluation & Formulation development.
7. Faster delivery:Sample order in stock and 3-7 days for bulk production.
8. We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS. Or you also can choose your own shipping forwarder.
9. After-Sale Service:
(1) International Authorized Third-Party Test For The Products You Demand.

 
Contact :
If you have any further questions or need a sample,Please do not hesitate to contact us.
 
ShenZhen Dieckmann Technology Development Co., LTD
ShenZhen Address:2floor,3 building, Maluan Make Place,2-10south of Jinlong Road, Pingshan New district,Shenzhen
Zip code: 518172
Tel: 86-755-28961872
Fax:0086-0755-84813563
  

Damnacanthal CAS No 477-84-9 for Traditional Medicine for Pharmaceuticals
Damnacanthal CAS No 477-84-9 for Traditional Medicine for Pharmaceuticals
Damnacanthal CAS No 477-84-9 for Traditional Medicine for Pharmaceuticals
Damnacanthal CAS No 477-84-9 for Traditional Medicine for Pharmaceuticals
Damnacanthal CAS No 477-84-9 for Traditional Medicine for Pharmaceuticals
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